Treatment sequencing involves the careful planning of the order in which therapies are administered to patients to maximize therapeutic benefits and minimize adverse effects. This process requires a deep understanding of disease progression, drug interactions, and individual patient responses. However, the challenges in treatment sequencing are significant. It often involves complex decision-making and sophisticated modeling to predict the most effective sequence of interventions. Health Technology Assessment (HTA) plays a crucial role in this process by evaluating the clinical and economic impacts of different sequencing strategies. Demonstrating the value of optimal treatment sequences can be difficult, as the benefits often manifest over long periods, requiring extensive data and advanced analytics to show improved patient outcomes and cost-effectiveness.
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